Silymarin introduction |
Silymarin features |
The role of Silymarin |
Silymarin notes |
Silymarin frequently asked questions are provided by pharmacists for Q&A reference. |
Machine / Work / Effect / Principle / Theory / Effectiveness / Benefit / Results
Silymarin introduction
Silymarin features
The role of Silymarin
Silymarin notes
Silymarin frequently asked questions are provided by pharmacists for Q&A reference.
Q-01. Who is suitable to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-02. For which symptoms is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） effective?
Q-03. Recommended dosage and method of taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-04. Should Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be taken before or after meals?
Q-04. How to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-04. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be taken on an empty stomach?
Q-05. How can I know if Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is effective?
Q-05. How long does it take to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） to see the improvement effect?
Q-06. Is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） different from other brands of Silymarin?
Q-07. What does the United States Pharmacopeia regulate the drug dissolution rate of Silymarin?
Q-08. Does the drug dissolution rate measured according to the US Pharmacopoeia method represent the bioavailability in vivo?
Q-08. The drug dissolution rate measured in vitro is 90%, while the dissolution rate of other drugs is 30%. Does it mean that taking 3 drugs of 30% is equivalent to 90%?
Q-10. Is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） medicine or food?
Q-10. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be used as preventive health care?
Q-10. Does Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） take a daily burden on the body?
Q-11. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be eaten for long-term maintenance?
Q-12. Are there any contraindications for taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-13. Can children take Silymarin (Hepana min)?
Q-14. How to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） for children with liver inflammation?
Q-15. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） during pregnancy or breastfeeding?
Q-16. Diuresis will occur after taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）. Is it normal?
Q-17. Is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） helpful to cancer patients?
Q-18. Patients with lung adenocarcinoma have been taking drugs for chronic diseases such as diabetes and hypertension for a long time; plus the patients themselves have prostate problems.
Q-18. After taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）, the patient takes longer to urinate. Is this situation normal?
Q-19. The patient has just undergone malignant tumor resection. Can the patient take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-20. Is it helpful for patients with liver cancer to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-21. The patient has a benign liver tumor and the liver index is a bit high. Is it suitable for patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-22. Cancer patients undergoing chemotherapy have impaired kidney function. How should patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-23. Is it suitable for people with a high liver Panel or liver B carriers to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-24. Do people with liver B liver need to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） as daily health care?
Q-25. Can drugs that inhibit the hepatitis B virus be taken at the same time with Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-26. Is it suitable for diabetic patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-27. I am a diabetic. The doctor took blood to check that the Creatinine （creatinine acid） value in the bleeding was high and the glomerular filtration rate was low.
The doctor said that continued deterioration may cause dialysis.
Is it helpful to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） now? How long does it take to see the effect?
Q-28. The patient's proteinuria, creatinine acid value is too high, and the value of glomerular filtration rate gradually decreases. It is recommended that patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） and cooperate with the doctor's follow-up examination. Based on feedback from physicians and patients.
Q-29. Can dialysis patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-30. I am already undergoing dialysis now. Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve kidney function? Can patients who have undergone kidney transplantation take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-31. Why does the improvement of liver function improve kidney function?
Q-32. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve Renal cyst?
Q-33. The patient is very old and carries the hepatitis C virus. The patient is hospitalized for liver inflammation and kidney inflammation due to overwork. The patient has edema and low albumin and needs a nutrition injection, and has no appetite.
Is it helpful for patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-34. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） if I have fatty liver? Will Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） effectively improve fatty liver? How to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-35. Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） lower the cholesterol index?
Q-36. I have three highs （hypertension, hyperlipidemia, hyperglycemia） and gout symptoms. Will taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve?
How is it recommended to take?
Q-37. The patient is currently hospitalized for liver disease. Can the patient take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-38. Can the patient take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） after an operation on the liver? Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） repair the liver?
Q-39. How should patients with "liver cirrhosis" take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-40. The patient's blood ammonia index is too high, showing dementia. Is it helpful for patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） at this time? Can the patient eat it?
Q-41. I often can't sleep, resulting in often staying up all night and poor sleep quality. Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） repair the liver? Can it make me fall asleep easier?
Q-42. People who often need to drink and socialize, need to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）? How is it recommended to take?
Q-43. The patient’s hemoglobin has been lowered and there is a suspected liver problem. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-44. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve the jaundice index?
Q-45. The patient is born with high Bilirubin. Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） lower the bilirubin value?
Q-46. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） for iron deficiency anemia?
Q-47. Can patients with immune system disorders take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-48. My gastrointestinal function is not good for a long time, and I am prone to bloating and indigestion. Sometimes I still can't improve it after taking gastric medicine for a long time. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Q-49. The patient has had gastrointestinal and flatulence problems for many years and has been taking gastrointestinal medicines for a long time.
Recently, the patient was introduced by the attending physician to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）, and her symptoms suddenly improved a lot, and she felt that the effect was better than gastrointestinal medicine.
Why can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve gastrointestinal function?
Silymarin introduction
Silymarin is the most natural extract found in the world that is beneficial to the liver and gallbladder.
European and American studies point out that milk thistle contains a variety of flavonoid components that protect the liver, collectively called Silymarin, and the main component is Silybin （or Silibinin）.
Research evidence shows that after animals and humans use silymarin （Silymarin）, Silybin has the highest detectable content in the liver, gallbladder, and bile and the longest residence time.
Therefore, Silymarin is most suitable for the maintenance of the liver and gallbladder.
However, the main active ingredient Silybin （or Silibinin） is insoluble in water or oil.
Silymarin has a low oral absorption rate in the human body, which has become the biggest bottleneck in the prevention and treatment of liver and gallbladder diseases.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） uses innovative biotechnology technology to effectively improve the absorption bottleneck of traditional Silymarin.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） successfully maintains Silymarin （Silymarin） in its natural structure, effectively increasing the bioavailability.
Silymarin (Hepana min) features：
1. Silymarin is a strong antioxidant flavonoid. Strong antioxidant.
2. Silymarin's main ingredient, silybin, has the best liver protection function.
3. Silymarin prevents liver damage caused by drugs and chemotherapy.
4. Silymarin is beneficial in regulating blood lipids.
5. Silymarin is beneficial to patients with fatty liver.
6. Silymarin helps reduce Aspartate Aminotransferase (AST / GOT) and Alanine Aminotransferase (ALT / GPT)
7. Silymarin can help patients with diabetes or poor blood sugar control improve blood sugar control.
8. Silymarin is beneficial to patients with liver disease, B liver band, C liver band and fatty liver patients.
9. Silymarin prevents cholestasis, frequent cholecystitis and gallstones.
10. Silymarin is beneficial for cancer, chemotherapy or electrotherapy patients to protect cells and reduce drug damage.
11. Silymarin is beneficial to patients with poor kidney function and kidney dialysis.
12. Silymarin is beneficial to patients who take drugs for a long time (chronic disease group).
13. Silymarin is beneficial to patients with alcoholism to protect the liver.
14. Silymarin is beneficial to patients with unexplained anemia (groups requiring iron supplementation).
15. Silymarin is beneficial to patients with heart atherosclerosis and lowers bad cholesterol LDL.
16. Silymarin is beneficial for patients with skin allergies and skin itching symptoms with abnormal liver and gallbladder metabolism
17. Silymarin is beneficial to patients with immune insufficiency to improve liver function.
The role of Silymarin：
1. Silymarin increases ribosomal protein production; promotes liver cell regeneration.
2. Silymarin helps protect the liver cell membrane structure and prevent the invasion of liver toxins.
3. Silymarin enhances the secretory function of liver cells and promotes the repair of inflamed liver cells.
4. Silymarin prevents chronic hepatitis from evolving into cirrhosis or chronic liver failure.
5. Silymarin prevents toxic substances (drugs, water pollution, air pollution) from harming liver cells.
Silymarin notes：
1. Silymarin increases bile secretion, which may cause diarrhea.
2. Pregnant women and breastfeeding women should not take Silymarin.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） frequently asked questions are provided by pharmacists for Q&A reference.
This Q&A is a reference provided by pharmacists based on pharmacy profession and experience.
If you have questions that are not in the Q&A, please feel free to consult.
If there is no improvement after taking it for a period of time, stop taking it immediately and ask a doctor to diagnose the cause.
Q-01. Who is suitable to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：The liver is an important organ for the human body to detoxify, regulate immunity and maintain normal physiological metabolism.
Physiological metabolism includes salt, cholesterol, and triglycerides, etc.
Every day the human body breathes, eats, or takes drugs for a long time （diabetes drugs, high blood pressure drugs, lipid-lowering drugs, chemotherapy drugs, etc.）, there will be pollution poisons or drug toxins residues entering the body.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） ingredient is Silymarin （Silymarin） extracted from natural plant milk thistle.
Silymarin has accumulated more than 4000 academic research reports in the world （PubMed National Library of America）.
Silymarin is recognized as the best liver-care ingredient in the world; it is suitable for adults over 18 years of age.
Many international academic research reports of Silymarin show that it is safe and can be taken for a long time
.
Q-02. For which symptoms is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） effective?
A：Silymarin mainly acts on liver, gallbladder and kidney.
Therefore, Silymarin can help to improve the symptoms of liver, gallbladder and kidney patients.
However, if the cause of the patient is more complicated, there is still no sign of improvement after taking Silymarin for a period of time.
Stop taking it immediately and ask a doctor to diagnose the cause.
Q-03. Recommended dosage and method of taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A： The common silymarin （Silymarin） has two kinds of prescription drugs （150 mng） and physician-pharmacist instructions （70 mg）.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is indicated by physicians and pharmacists （70 mg）.
In past animal experiments, it was found that under the same dose of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）, the blood concentrations of different individual animals were not completely the same.
There will be individual differences in the blood concentration of animals （this is reasonable）.
Therefore, a few people take the dosage of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）： 1 capsule at a time, 3 times a day will also be effective.
However, in order to ensure that the effect can be exerted, it is recommended that the initial dose of the patient must be 2 capsules at a time, 2 or 3 times a day.
The dose is still lower than the prescribed dose, and patients can take it for a long time without worry.
Q-04. Should Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be taken before or after meals?
How to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be taken on an empty stomach?
A：Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） has mild ingredients and can be taken before or after meals, without hurting the intestines and stomach. （Can be taken at any time.）
It is best to swallow with drinking water.
If there are religious considerations, the shell of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） capsules is HALAL certified.
For those who are vegan or who are not good at swallowing, the capsule can be opened and swallowed directly with drinking water and powder.
But be careful not to be choked by the powder!
The powder has a plant taste, with a bit of sweetness and bitterness.
If you are lying in bed or inserting a nasogastric tube, you can feed the powder mixed food or feed the mixed liquid through the nasogastric tube.
Suggested daily health care dosage： 1 or 2 capsules at a time; 2 or 3 times a day.
Depends on personal physique and improvement situation.
If you have liver, gallbladder, or kidney symptoms that require treatment, please refer to the dosage recommended in this Q&A corresponding to the situation.
If you have any questions, please feel free to email us.
Q-05. How can I know if Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is effective?
How long does it take to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） to see the improvement effect?
A：Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is an excellent and qualified product manufactured by Pic/s GMP pharmaceutical factory.
Whether it can improve the patient's disease can be judged according to the hospital's test data.
For example： blood tests and liver, gallbladder and kidney ultrasound examinations, and other methods to judge.
According to actual experience, if it is under the indication of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） dosage： 2 capsules at a time; 3 times a day.
Usually, patients can draw blood to check the comparison data within 14 days.
Q-06. Is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） different from other brands of Silymarin?
A： Academic research reports can find that "low oral bioavailability" is the key bottleneck in the treatment of diseases with Silymarin.
The United States Pharmacopeia does include the Silymarin contained in Milk Thistle.
The United States Pharmacopoeia has standardized Silymarin test eligibility criteria, among which the dissolution rate of the test items related to the bioavailability is the key.
Silymarin must be dissolved in simulated physiological conditions before it can be absorbed by the body's gastrointestinal tract.
Therefore, the United States Pharmacopoeia stipulates that the dissolution rate must be at least 75% to be a qualified Silymarin drug.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） can completely pass all the test items in the US Pharmacopoeia, which is the dissociation rate.
However, none of the commercially available Silymarin foods can pass the U.S. Pharmacopoeia dissolution rate test.
The dissociation rate measured in vitro by the United States Pharmacopoeia cannot be directly converted into the bioavailability in vivo.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） commissioned the medical school to perform an animal test analysis of the bioavailability and compare it with the pharmaceutical company B and the Brand drug.
The dissolution rate of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） in the United States Pharmacopeia is about 98%.
The dissolution rate of the US Pharmacopoeia of Pharmaceutical Factory B is about 34%, so the dissolution rate of the US Pharmacopoeia is about 3 times different.
The actual implementation of Bioavailability Animal Test Silymarin blood concentration of Pharmaceutical Factory B differed by 35 times.
The US Pharmacopoeia dissolution rate of Brand drugs is about 78%.
The actual blood concentration of the Brand drug in the animal test is 8.5 times different.
Indicates the physical availability rate of taking 1 capsule of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） （70 mg）.
=Silymarin 2450 mg （35 tablets） from Pharmaceutical Factory B.
=Brand drug Silymarin 595 mg （8.5 tablets）.
Therefore, the key to the efficacy of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is far superior to other Silymarin of the same ingredient.
At the same time, Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） has commissioned a professional company to complete an oral toxicological safety analysis report.
It is still safe to take 6.4, 19.2, and 51.2 times the normal recommended daily dose for three consecutive months.
Therefore, Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is of course different from other commercially available Silymarin products with the same ingredients.
Detailed comparison of the dissolution rate of Silymarin products in various countries.
Q-07. What does the United States Pharmacopeia regulate the drug dissolution rate of Silymarin?
A：The medicine must be dissolved before it can be absorbed by the body.
In other words, the bioavailability of medicines is the most important key that affects the efficacy.
However, the implementation of the bioavailability of drugs must be tested batch by batch when the drug is produced batch by batch.
This inspection is very time-consuming and sacrifices many animals.
Therefore, under humanitarian considerations, the United States Pharmacopeia is designed to simulate the human gastrointestinal absorption environment.
The United States Pharmacopeia sets the dissolution conditions and standards in vitro.
The U.S. Pharmacopoeia requires that each batch of medicines need to perform dissociation tests in accordance with the methods and conditions of the U.S. Pharmacopoeia instead of animal testing.
At present, the capsules or lozenges of the United States Pharmacopeia have qualified dissolution rate standards set by the United States Pharmacopeia.
E.g：The US Pharmacopoeia dissolution rate of Silymarin must be at least 75%.
That is, if 100 mg （Silymarin） is taken orally, at least 75 mg （Silymarin） must be dissolved to be a qualified drug.
The higher the dissolution rate, the higher the amount that can be absorbed by the body.
The higher the bioavailability, the better the natural effect.
The key to the difference in efficacy between Generic Drugs and Brand Drugs produced by different pharmaceutical companies is the difference in dissolution rate.
Q-08. Does the drug dissolution rate measured according to the US Pharmacopoeia method represent the bioavailability in vivo?
E.g：The drug dissolution rate measured in vitro is 90%, while the dissolution rate of other drugs is 30%. Does it mean that taking 3 drugs of 30% is equivalent to 90%?
A：The dissociation rate measured in vitro by the United States Pharmacopoeia cannot be directly converted into bioavailability in vivo.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） commissioned the medical school to perform an animal test analysis of the bioavailability and compare it with the pharmaceutical company B and the Brand drug.
The dissolution rate of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） in the United States Pharmacopeia is about 98%.
The dissolution rate of the US Pharmacopoeia of Pharmaceutical Factory B is about 34%, so the dissolution rate of the US Pharmacopoeia is about 3 times different.
The actual implementation of Bioavailability Animal Test Silymarin blood concentration of Pharmaceutical Factory B differed by 35 times.
The US Pharmacopoeia dissolution rate of Brand drugs is about 78%.
The actual blood concentration of the Brand drug in the animal test is 8.5 times different.
Indicates the physical availability rate of taking 1 capsule of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） （70 mg）.
=Silymarin 2450 mg （35 tablets） from Pharmaceutical Factory B.
=Silymarin 595 mg （8.5 tablets） of Brand drug.
Therefore, the key to the efficacy of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is far superior to other Silymarin of the same ingredient.
At the same time, Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） has commissioned a professional company to complete an oral toxicological safety analysis report.
It is still safe to take 6.4, 19.2, and 51.2 times the normal recommended daily dose for three consecutive months.
Drugs should be taken as directed, and abuse is prohibited.
Q-10. Is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） medicine or food?
Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be used as preventive health care?
Does Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） take a daily burden on the body?
A： Silymarin is only used as a medicine in Germany and China, and it is used as a food product in other countries. （Including： United States, United Kingdom, France, Russia, Japan, Australia,... etc...）
Silymarin is sold in major cosmeceuticals and mass merchandise stores.
The accumulated academic research of Silymarin has published more than 4000 papers （PubMed National Library of America）.
You can check the safety and efficacy of Silymarin online!
Since the nerve density of the liver itself is not high, once the disease occurs, it will be more serious.
The liver must deal with large amounts of air, diet, and drug toxin residues every day.
The liver is the body's largest detoxification and metabolism organ.
Almost all diseases of the body are related to liver metabolism.
Therefore, we should usually pay attention to maintaining a high-quality liver environment, so that damaged liver cells have the opportunity to regenerate and repair.
Therefore, the health of the liver is a daily necessity.
Q-11. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be eaten for long-term maintenance?
A：Long-term liver maintenance is necessary.
Because the liver cells' daily metabolism and detoxification work will be impaired.
God has given the human liver, which is the only reproducible organ of the human body.
However, the regeneration of liver cells must be established in a healthy and high-quality liver environment.
Therefore, the maintenance of the liver is very important.
Liver disease is caused by long-term accumulation.
Therefore, we must pay attention to the health of the liver.
Q-12. Are there any contraindications for taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A： Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is best swallowed with drinking water, not fruit juice or acidic beverages.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） should be cautious in the use of organ transplant patients!
Because organ transplant recipients generally take immunosuppressive agents.
The liver is the first-line immune regulatory organ of the human body, and awakening the liver’s immunity may increase the risk of organ rejection.
Therefore, when organ transplantation recipients take Silymarin, they should first ask the doctor for evaluation and cooperate with the doctor for diagnosis and follow-up at any time.
Q-13. Can children take Silymarin (Hepana min)?
A：Not recommended for babies.
Children under 18 should consult a physician or pharmacist before taking it.
Patients should be prescribed by their doctor or pharmacist according to their symptoms and age.
Q-14. How to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） for children with liver inflammation?
A：If the patient is over 18 years old and has severe liver inflammation.
The best initial dose： 2 capsules at a time, 3 times a day.
The patient waits for the liver inflammation index to drop; then slowly adjust the dose.
When the dose is lowered and the inflammation index rises, it is necessary to return to the original dose.
There are many reasons for children's liver inflammation, and there is no sign of improvement after taking it for a period of time.
Stop taking it immediately and ask a doctor to diagnose the cause.
Q-15. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） during pregnancy or breastfeeding?
A： Although Silymarin is highly safe, it is not recommended for the first five months of pregnancy.
If you need to use it due to a medical condition, you should consult a physician for judgment before use.
In addition, according to Pharmacokinetics to analyze the time required for blood metabolism, Silymarin should be avoided as much as possible within three hours before breastfeeding.
It has been reported that Silymarin enters the blood after being absorbed.
In addition to the highest concentration in the liver and gallbladder, a small amount will also enter the breast.
Therefore, if there is no urgent need, avoid taking it as much as possible during breastfeeding.
Q-16. Diuresis will occur after taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）. Is it normal?
A：A small number of people take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） at the initial stage to have a diuretic effect.
Because Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） ingredient Silymarin has a protective effect on the kidneys after absorption.
So it will feel diuretic and the urine will be clearer!
However, the diuretic sensation is only after the initial use, and it will disappear after a period of time.
It can help to remove toxins accumulated in the body in the past, and after the removal, there will be no feeling of diuresis.
So after taking it for a period of time, the feeling of diuresis will disappear.
Patients with prostatic hypertrophy should pay attention when taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）. （Because of the diuretic effect of Silymarin.）
Q-17. Is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） helpful to cancer patients?
A： Although Silymarin is not capable of directly targeting cancer cells.
However, the chemotherapy drugs used by cancer patients during the treatment process usually cause damage to the liver, kidneys and other organs and tissues.
Silymarin has hundreds of academic research reports showing that it has a protective effect on organ tissue damage caused by chemotherapeutic drugs.
Due to the strong toxicity of chemotherapy drugs, the recommended dose for patients： 1 to 2 capsules at a time; 3 times a day.
The patient's dosage depends on the severity of symptoms.
Q-18. Patients with lung adenocarcinoma have been taking drugs for chronic diseases such as diabetes and hypertension for a long time; plus the patients themselves have prostate problems.
After taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）, the patient takes longer to urinate. Is this situation normal?
A：Silymarin because it protects the kidneys.
Patients who take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） at the initial stage may have diuretic effects due to the protection of the kidneys.
Therefore, the urine output of patients will increase in the initial stage.
Therefore, patients with prostatic hypertrophy may cause inconvenience when taking Silymarin.
Please pay attention to patients with prostatic hypertrophy when taking Silymarin!
Patients can stop taking Silymarin or reduce the dosage or frequency to improve the diuretic problem.
The problem of improving diuresis is related to the dosage of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Patients who take Silymarin for a long time will still see the effect of protecting liver, gallbladder and kidney.
So patients don’t have to worry.
In addition, it is recommended that patients with prostatic hypertrophy should not hold back urine; otherwise, it will be more difficult to urinate.
Therefore, during the initial period of taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） in patients with prostatic hypertrophy, they have to urinate if they want to urinate.
Q-19. The patient has just undergone malignant tumor resection.
Can the patient take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：Maintaining the liver is a daily health care task; not to mention that patients with tumors have undergone various drug treatments or resections.
The health of cancer patients is more important.
Tumors come from cell mutations.
The reason for the mutation of cells may be long-term or inertial contact with "certain substances"; the genes of the cells mutate into cancer cells.
Therefore, the liver is the only organ in the body that can "detoxify and reduce toxins".
If the liver functions well, it can reduce the chance of toxins' damage to cells and cell mutations.
Q-20. Is it helpful for patients with liver cancer to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：Tumor growth is often accompanied by inflammation.
Inflammation is not only beneficial to the spread and growth of tumors, but also causes uncomfortable side effects for patients.
It has been reported that Silymarin has the highest concentration distributed in the liver and gallbladder after being absorbed; at the same time, Silymarin has the effect of inhibiting liver inflammation.
Therefore, Silymarin should be helpful to improve liver inflammation in patients with liver cancer.
But Silymarin may only improve the quality of life of liver cancer patients.
Silymarin has limited effectiveness in inhibiting tumors.
Therefore, Silymarin can be used as an adjuvant for adjuvant therapy, not as the main therapeutic drug.
Details should be discussed and evaluated with the oncologist.
If you need to use Silymarin, the recommended dosage： 2 capsules at a time, 3 times a day.
Q-21. The patient has a benign liver tumor and the liver index is a bit high.
Is it suitable for patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：Benign liver tumors may be liver hydromass or liver abscesses; patients must cooperate with physicians for follow-up treatment.
If the patient has liver inflammation, he should take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Suggested dosage： 1 to 2 capsules at a time; 3 times a day.
The dosage depends on the individual's physique.
Q-22. Cancer patients undergoing chemotherapy have impaired kidney function.
How should patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：Chemotherapy drugs are generally more toxic.
Acute kidney injury （AKI） occurs in 20-30% of cancer patients receiving chemotherapy （for example： Cisplatin, Methotrexate）.
In addition to increasing the risk of patients, AKI can also cause treatment to be interrupted and affect the effect of cancer treatment.
Damage to kidney function includes glomeruli, renal tubules, interstitial cells and renal capillaries.
Clinical manifestations include increased serum creatinine, decreased glomerular filtration rate, or other inflammation; in severe cases, kidney dialysis is necessary.
Therefore, Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） must be taken during chemotherapy to protect the liver and kidneys.
Suggested dosage：
1. When the liver and kidney are severely damaged; 2 capsules at a time; 3 times a day.
2. When slightly damaged; 2 capsules at a time; 2 times a day.
During the period of taking, blood can be taken with the hospital to check whether creatinine acid and glomerular filtration rate have been improved.
It takes time for patients to repair their organs due to chemotherapy. It is recommended to take it for a long time.
Q-23. Is it suitable for people with a high liver Panel or liver B carriers to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：High liver inflammation index is the carrier of the hepatitis B virus; patients have a high probability of developing liver cirrhosis and liver cancer.
Therefore, the patient must lower the hepatitis index.
It is safer if the patient’s liver is not inflamed.
Silymarin has the effect of stabilizing the liver cell membrane, preventing the hepatitis virus from invading new liver cells.
Suggested dosage： 2 capsules each time; 2 or 3 times a day.
After taking it continuously for more than 2 years, there have been records of patients clearing hepatitis B virus DNA.
Carriers of hepatitis B virus should have the patience to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） for a long time.
Q-24. Do people with liver B liver need to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） as daily health care?
A：No doubt!
People with liver B liver should take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） more than normal people!
The mechanism of Silymarin inhibiting the spread of hepatitis virus to new liver cells has been reported in many international academic papers.
At the same time, the liver is the body's immune regulatory organ.
Strong immunity helps fight the hepatitis virus.
Therefore, patients with hepatitis B need to take it more; especially those with liver inflammation need to take it more.
Suggested dosage： 2 capsules each time; 2 or 3 times a day.
Patients should be patient and take it for a long time.
Q-25. Can drugs that inhibit the hepatitis B virus be taken at the same time with Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：At present, oral drugs to inhibit the hepatitis B virus include Lamivudine, Adefovir, Telbiyudine, Entecavir, Tenofovir, and other drugs.
At present, there are no reports of contraindications for combined treatment of Silymarin and hepatitis B virus drugs.
Instead, many papers show that Silymarin and hepatitis B virus-inhibiting drugs are combined to treat the hepatitis B virus.
Silymarin has the function of stabilizing liver cell membrane in many academic reports.
Therefore, hepatitis B virus carriers can take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） and drugs that inhibit the hepatitis B virus at the same time.
Does the patient take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） for better results?
Patients can cooperate with the physician's liver function test and virus count test to understand the treatment situation.
Suggested dosage：
1. Acute or high virus count complicated with liver inflammation; 2 capsules each time; 3 times a day.
2. Other conditions; 2 capsules each time; at least 2 times a day.
Q-26. Is it suitable for diabetic patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：Physiologically, the liver and pancreas play a role in maintaining constant blood sugar.
When hypoglycemia occurs, the liver breaks down the stored glycogen and releases it into the blood.
When high blood sugar occurs, the liver not only converts blood sugar into glycogen storage but also controls the pancreas to secrete insulin to lower blood sugar.
Especially type II diabetes is mostly caused by metabolic disorders.
The patient’s metabolic disorders may be caused by poor liver and gallbladder function and chronic inflammation of the pancreas.
Bile enters the pancreas （head） through the bile duct and then drains into the duodenum.
Chronic inflammation of the pancreas stems from poor detoxification of the liver, which leads to the poor gall bladder.
Long-term stimulation of the pancreas by incompletely detoxified bile can cause inflammation of the pancreas.
The symptom of chronic chronic inflammation of the pancreas is unstable blood sugar control.
Long-term chronic inflammation of the pancreas presents unstable blood sugar control.
If it does not improve the inflammation of the pancreas.
Allow the pancreas to continue to inflame, and pancreatic cancer may occur in severe cases.
For this reason, 70% of pancreatic cancers occur in the head of the pancreas at the junction of the pancreatic duct and the bile duct.
Therefore, diabetic patients （especially diabetic type II patients） need to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） to improve liver and gallbladder function; further reduce the chance of pancreatic inflammation.
Therefore, the blood sugar control of diabetic patients will be more stable!
Suggested dosage： 1 to 2 capsules at a time, 3 times a day.
The patient's dosage depends on the individual's physique.
After the patient has taken it for a period of time and after the blood sugar control has stabilized, consult with the physician whether the dose can be lowered.
If the patient does not see any signs of improvement after taking it for a period of time, he should stop taking it immediately and ask a doctor to diagnose the cause.
Q-27. I am a diabetic.
The doctor took blood to check that the Creatinine （creatinine acid） value in the bleeding was high and the glomerular filtration rate was low.
The doctor said that continued deterioration may cause dialysis.
Is it helpful to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） now?
How long does it take to see the effect?
A：According to statistics, every two diabetic patients; the last one will have a kidney dialysis.
Currently, there is no effective medicine to treat the problem of persistent deterioration of renal function.
Commonly used diuretics are only auxiliary methods and cannot be fully controlled.
According to academic literature reports, Silymarin can indeed improve chronic kidney disease （CKD） caused by diabetes.
Therefore, it is recommended to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Suggested Dosage： 2 capsules each time; 2 or 3 times a day.
One month later, the patient will cooperate with the doctor to take blood tests to check whether the kidney function problem has gradually improved.
If kidney function improves, it is recommended to take it for a long time.
Kidney repair takes time.
At present, many patients have experienced significant improvement in renal function or no need for dialysis after taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Therefore, it is recommended to take it and cooperate with the doctor's follow-up treatment.
Q-28. The patient's proteinuria, creatinine acid value is too high, and the value of glomerular filtration rate gradually decreases.
It is recommended that patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） and cooperate with the doctor's follow-up examination.
Based on feedback from physicians and patients.
A：According to academic research reports, one out of every two diabetic patients will have a kidney dialysis due to Chronic Kidney Disease （CKD）.
Among them, proteinuria, creatinine acid, and glomerular filtration rate are indicators to assess kidney function and whether to dialysis.
Although many patients are not yet at the stage of dialysis, the creatinine acid value continues to be high and the glomerular filtration rate continues to decrease.
At present, there is no effective treatment drug in the world.
But recently, I have received feedback from doctors and patients.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） can effectively improve proteinuria, creatinine acid and glomerular filtration rate.
So provide information reference.
Patients taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） should still cooperate with the doctor's blood test and follow-up treatment.
Suggested dosage：
1. Abnormal renal function： 2 capsules each time; 3 times a day; either before or after meals.
2. Long-term maintenance after stabilization; recommended dose： 2 capsules each time; 2 times a day.
Q-29. Can dialysis patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：The cause of kidney dialysis is that the body has accumulated too much toxins that cannot be metabolized and discharged.
Therefore, hemodialysis must be used to directly wash out the waste in the blood.
The liver is the body's detoxification organ, especially the metabolism and detoxification of urea （Urea）.
Poor liver function and the inability to fully detoxify will increase the burden on the kidneys.
Therefore, we must pay attention to the metabolism of liver, gallbladder, and kidney.
At the same time, patients with dialysis are often accompanied by insufficient hemoglobin, platelets, albumin and immune function.
The liver is the organ that controls hemoglobin, platelets, albumin and immune function.
At present, there is no medicine to treat kidney cells to regain their function, and they can only try to maintain it and not deteriorate.
According to actual experience, if Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） can improve liver, gallbladder, and kidney functions.
According to the physiological mechanism of the liver, the patient's hemoglobin and platelets should be the first to increase.
You can clearly see that the patient's face gradually fades from the dullness.
However, it is mainly based on the test data before and after taking to know whether there is progress （improvement）.
For patients undergoing dialysis, please consult your doctor first and cooperate with the doctor's follow-up treatment before taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） only has a supporting role and should not have high expectations.
If you need to use it, the recommended dosage is： 1 or 2 capsules each time; 2 or 3 times a day.
Patients should adjust the dosage according to the doctor's instructions.
Q-30. I am already undergoing dialysis now.
Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve kidney function?
Can patients who have undergone kidney transplantation take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：There is not enough data to answer at this time.
But according to the patient's experience in taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
General dialysis patients are taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）
Suggested Dosage： 2 capsules each time; 2 or 3 times a day.
One month later, the patient's complexion gradually faded and improved from dullness.
Three months later, the patient's face was almost the same as a normal person.
It is not yet certain whether the improvement of the patient's complexion is related to the improvement of renal function.
It is only the appearance of the patient to observe the improvement and progress.
At the same time, remind patients that the kidney is different from the liver; the kidney cannot regenerate.
If the patient has been severely dialysis for a long time, at most, it can only improve the control but cannot fully restore health.
Therefore, patients should not expect too much.
In addition, patients who have undergone kidney transplantation are advised not to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）!
Because Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） will restore the liver's immune recognition function.
I am afraid that it will cause rejection of the patient's kidney transplantation.
It is recommended to consult your attending physician before taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） and cooperate with the physician's diagnosis.
Q-31. Why does the improvement of liver function improve kidney function?
A：Because the liver is responsible for the detoxification and metabolism of the body every day.
Especially the water-soluble waste after detoxification is mainly excreted through the kidneys.
Therefore, if the liver is completely detoxified, the burden and damage to the kidneys will be reduced.
Although the kidneys cannot regenerate, they have some self-healing and repairing functions.
Therefore, if the liver is good, the kidney function will be improved naturally.
It is important to provide a clean environment for the kidneys to heal and repair themselves.
Q-32. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve Renal cyst?
A： There is currently no clinical medicine to treat Renal cyst.
The general treatment method of doctors is follow-up observation, and if there is an abnormality, the operation will be arranged.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） can protect the kidneys.
However, it is not clear whether Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） can improve Renal cyst.
Therefore, there is no suitable drug treatment at present, it is recommended to try!
At least renal function can be improved, but patients should also cooperate with doctors for follow-up treatment.
Q-33. The patient is very old and carries the hepatitis C virus.
The patient is hospitalized for liver inflammation and kidney inflammation due to overwork.
The patient has edema and low albumin and needs a nutrition injection, and has no appetite.
Is it helpful for patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：Carriers of hepatitis virus should not be overworked.
If there is usually liver inflammation, be more careful!
Acute hepatitis or subacute hepatitis will cause the liver's detoxification function to decrease and the ability to produce albumin （Albumin）.
The liver cannot effectively detoxify, causing toxins to flow into the kidneys; causing kidney inflammation and edema.
Delaying the condition for too long will lead to liver cirrhosis, ascites and kidney failure, which may be life-threatening.
Therefore, it is correct to seek medical treatment as soon as possible in the hospital.
At present, the injection of albumin by patients is only a temporary measure.
The focus of treatment is to reduce liver inflammation first to improve other symptoms!
It is recommended that the information on Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） be provided to the attending physician for reference.
And inform the doctor that Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is currently the only liver maintenance medicine that meets the latest U.S. Pharmacopoeia Silymarin specifications.
Obtain the doctor's approval before taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Suggested dosage： 2 capsules at a time; 3 times a day.
If it is effective, the patient's life phenomenon should be gradually stabilized and appetite restored within a few days.
After 14 days, the patient can cooperate with the resident to take a blood test for liver inflammation, albumin and other data.
Q-34. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） if I have fatty liver?
Will Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） effectively improve fatty liver?
How to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A： At present, there is no ideal and effective treatment drug for fatty liver in the world.
If the patient has fatty liver accompanied by liver inflammation, it must be actively treated and controlled.
Because long-term chronic liver inflammation can lead to liver cirrhosis and even liver cancer.
There have been many research reports on Silymarin that have proven to improve fatty liver.
The dosage of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is 70 mg of Silymarin per capsule.
The clinical prescription drug contains 150 mg of Silymarin per capsule.
Therefore, the normal dose of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is safe to take for a long time.
Suggested dosage：
1. Patients with mild or moderate fatty liver; 1 to 2 capsules at a time; 3 times a day.
2. Severe fatty liver; 2 capsules at a time; 3 times a day.
After the patient has taken it for three months, he can ask the doctor to improve the situation by ultrasound examination.
According to experience, patients who take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） seriously should all improve.
Q-35. Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） lower the cholesterol index?
A：Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is used to improve liver, gall bladder and kidney function, not a treatment for cholesterol.
Therefore, silymarin （heparin） does not work like statins; it directly inhibits HMG-CoA reductase and effectively hinders the synthesis of cholesterol.
Therefore, statins can quickly lower blood cholesterol.
However, patients taking Statins drugs know that Statins drugs have a certain degree of side effects on the liver.
Therefore, patients taking Statins must cooperate with physicians to track liver function.
Cholesterol and triglycerides of normal human physiology are metabolized, decomposed and synthesized in the liver.
If the patient has high cholesterol and triglycerides due to abnormal liver function.
After patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） to solve liver problems, it is possible to improve symptoms of high cholesterol and triglycerides.
The patient should cooperate with the physician to diagnose the cause in detail and prescribe medicine to the symptom.
If the patient’s symptoms are of unknown cause, it is recommended that the patient should continue to take cholesterol-lowering drugs.
Patients should not directly substitute Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） for the medicine prescribed by the doctor.
Patients can take it at the same time, which not only directly controls cholesterol but also protects the liver.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） can protect the liver from damage from lipid-lowering drugs.
At the same time, after the liver problem is improved, the metabolism, decomposition and synthesis of cholesterol and triglycerides will be more normal.
Suggested dosage： 1 or 2 capsules each time; 2 or 3 times a day. Basic dose.
Patients can adjust according to their physical condition.
If the patient does not see any signs of improvement after taking it for a period of time, he should stop taking it immediately and ask a doctor to diagnose the cause.
Patients should not keep taking it blindly.
In the initial stage of blood sugar control, Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） cannot be used to control blood sugar alone.
After taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）, it was revealed from the patient's test report.
1. The value of Triglycerides （TG） decreases.
2. The value of High-density lipoprotein （HDL） increased.
Q-36. I have three highs （hypertension, hyperlipidemia, hyperglycemia） and gout symptoms. Will taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve?
How is it recommended to take?
A： Hypertension, hyperlipidemia, hyperglycemia and gout are all related to liver metabolism.
Most patients with hypertension are not easy to find the cause.
The coordinated role of the liver and pancreas is to control the blood sugar level in the human body.
When the blood sugar level is low, Glycogen stored in the liver will be broken down into glucose to increase the blood sugar level.
When the blood sugar level is too high, the liver will not only store glucose to synthesize glycogen （Glycogen）, but also stimulate the pancreas to secrete insulin （Insulin） to lower the blood sugar level.
The metabolism of cholesterol, triglycerides or uric acid in the human body is also carried out in the liver.
The liver can convert Uric acid into non-toxic urea, which is then excreted by the kidneys.
Therefore, when patients take cholesterol-inhibiting drugs and uric acid drugs for a long time.
Patients must regularly take blood to track and check liver and kidney function.
Academic research report statistics： In the end, one out of every two diabetic patients will have to have kidney dialysis.
Therefore, patients should prevent and strengthen health care as early as possible.
Suggested dosage：
1. Abnormal liver or kidney function; 2 capsules each time; 3 times a day. Either before or after meals.
2. After the symptoms have stabilized, continue to take it for a long time. 2 tablets each time; 2 times a day.
Q-37. The patient is currently hospitalized for liver disease.
Can the patient take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A： At present, all hospitals, clinics, and pharmacies have different brands of Silymarin medicines. Their curative effects are universal and cannot be recognized by doctors and pharmacists.
In fact, there are not many other liver-maintaining drugs available in the market.
So Silymarin is sold as food.
Although Silymarin is recognized as the best ingredient for liver maintenance in the world.
However, the low oral bioavailability of Silymarin is the bottleneck of treatment.
The company tested and analyzed the results in accordance with US Pharmacopoeia standards.
At present, the only Silymarin that can pass the US Pharmacopoeia inspection specifications is Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）!
Therefore, it is recommended to provide Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） drug information to the attending physician for reference.
Please inform the physician that Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） has broken through the bottleneck of low Bioavailability, with a bioavailability rate of 98%.
If the attending physician fully understands it, he should not object to taking it.
Suggested dosage： 2 capsules at a time; 3 times a day.
Patients should cooperate with physicians to treat and track blood data.
If the doctor has any questions, please email for consultation and discussion.
Q-38. Can the patient take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） after an operation on the liver?
Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） repair the liver?
A：The liver is the only regenerating organ in the human body.
Therefore, no matter what the reason is, the liver itself has the ability to heal itself!
However, the liver must first resolve the causes of liver disease and provide a high-quality environment for the liver to heal itself.
For example, the gallbladder is cut off in most people with biliary disease.
But the actual gallbladder disease is caused by the poor liver.
If the patient removes the gallbladder, it is just to deal with the pain.
To "treat the head when the headaches, treat the foot when the foot hurts" is not a good solution to tackle the present problem of disease.
The fundamental problem of the patient's disease has not been resolved.
Therefore, it is very important to provide a high-quality self-healing environment for the liver to regenerate liver cells.
Suggested dosage： 2 capsules each time; 3 times a day.
If it can reduce the patient's liver inflammation and improve the liver environment.
Within one month, the patient's blood test report can see the improvement effect.
Every three months, the patient cooperates with the doctor’s ultrasound examination to understand the patient’s liver regeneration and repair status.
According to actual observations, liver repair takes at least six months to several years. It is recommended to take it for a long time.
Dosage： 1 or 2 capsules each time; 2 or 3 times a day.
The liver's self-healing depends on the degree of damage and the quality of the liver's environment.
Q-39. How should patients with "liver cirrhosis" take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：The liver is the only organ in the human body that can regenerate.
However, the regeneration of liver cells must be based on providing a high-quality repair environment for liver cells, so that liver cells can be regenerated.
Therefore, the normal maintenance of the liver is very important.
If the patient's condition has progressed to cirrhosis.
Based on case experience, it is recommended to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Suggested dosage： 2 capsules at a time; 3 times a day.
Patients should continue to take it for a period of time （at least half a year）.
Because after improving the liver environment, it takes a while to regenerate and repair liver cells!
During the patient taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
The patient cooperates with the physician's ultrasound examination every three months to check the improvement.
If the condition improves, patients with liver cirrhosis must be persevering when taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Otherwise, there is currently no drug to cure liver cirrhosis in the world.
Healing liver diseases mainly depends on the self-healing and regeneration of liver cells!
Q-40. The patient's blood ammonia index is too high, showing dementia.
Is it helpful for patients to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） at this time?
Can the patient eat it?
A：Ammonia is a toxic metabolite.
The main toxic effect of ammonia is on the brain nerves, so it can cause patients to coma, lethargy or dementia!
Ammonia in the human body is processed in the liver; ammonia is converted into non-toxic urea through the Urea Cycle reaction, and then excreted by the kidneys.
If the patient has symptoms of ammonia toxicity, it means that the liver has been severely damaged, which may affect life.
It is recommended that patients take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） as soon as possible.
Suggested dosage： 2 capsules at a time; 3 times a day.
If the patient has inserted the nasogastric tube, the capsule can be opened and the powder mixed fluid or food can be poured through the nasogastric tube.
Patients should consult their attending physician before taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Please inform the physician that Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is the Silymarin with the highest dissolution rate in the world.
The patient must ask a physician for follow-up treatment.
Q-41. I often can't sleep, resulting in often staying up all night and poor sleep quality.
Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） repair the liver?
Can it make me fall asleep easier?
A： Poor sleep quality should have nothing to do with staying up late.
According to the theory of traditional Chinese medicine： 11 pm to 1 am; vital energy and blood enter the Liver Meridian.
It means that this period is the time for the liver to repair itself.
Therefore, staying up late and eating supper means that the liver has no chance to rest.
So it is best not to stay up late and eat supper.
Taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） to repair the liver is originally the function of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
But whether it can improve the quality of sleep is the key.
According to observation; the actual situation of patients taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Patients taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） will have two feelings at the initial stage：
1. The patient wants to sleep very much, sleeps deeply, but not tired.
After one or two weeks, this feeling of wanting to sleep will gradually disappear, and the quality of sleep will also improve.
2. The patient is very energetic, not wanting to sleep but not getting tired.
Both of the above can happen, and it may be different depending on your physique.
Basically, the quality of sleep is not good. It is recommended to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）. Start by repairing liver cells.
Suggested dosage： 1 or 2 capsules each time; 2 or 3 times a day. Basic dose.
Patients can adjust according to their own physical conditions.
Q-42. People who often need to drink and socialize, need to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
How is it recommended to take?
A： Drinking can hurt your body; try not to drink.
But if it is necessary to socialize and drink, be sure to protect the liver first.
It is recommended to take two tablets before drinking.
After drinking, take two more capsules at least two hours after the previous dose.
It can protect the liver and avoid the hangover problem of the next day.
Q-43. The patient’s hemoglobin has been lowered and there is a suspected liver problem. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A：The patient's hemoglobin decreased for unknown reasons.
Patients should first ask a physician to diagnose the cause and prescribe medicine to the symptoms.
If the doctor is still unable to diagnose the cause, it is recommended to try Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Because Western medicine believes that the liver is an organ that controls the blood volume of the human body.
TCM theory： liver storing blood and liver controlling dispersion/ liver governing regulating.
Therefore, the liver is good, and the complexion will appear healthy and ruddy.
If the liver function is checked, the liver function data is normal but often feel tired.
It may be caused by liver disease, but it has not reached the level of severe symptoms.
Suggested dosage： 1 or 2 capsules each time; 2 or 3 times a day.
If the patient has not seen any signs of improvement after taking it for one month.
It is recommended that patients ask a physician to diagnose the cause in detail or increase the dose of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Suggested dosage： 2 capsules each time; 3 times a day.
Patients must cooperate with physicians to track treatment and test blood data to avoid delaying the condition.
Q-44. Can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve the jaundice index?
A： Patients with unexplained jaundice should first ask a doctor to diagnose the cause.
Unexplained reasons may be tumors or unexplained obstruction of the biliary tract causing jaundice.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） has a good effect on improving jaundice caused by liver and gallbladder problems.
If only chemotherapy drugs temporarily damage the liver.
Taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） should quickly reduce the jaundice index and repair the liver.
1. Early stage.
Suggested dosage： 2 capsules at a time, 3 times a day.
2. If the patient's jaundice has been significantly improved.
Suggested dosage： 2 capsules at a time; 2 times a day.
3. Normal people
Suggested dosage： 1 capsule at a time; 3 times a day. Also effective.
Patients must pay attention to evaluation and observation.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is a very safe liver maintenance medicine.
If the patient does not see any signs of improvement after taking it for a period of time, he should stop taking it immediately and ask a doctor to diagnose the cause.
Q-45. The patient is born with high Bilirubin.
Can taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） lower the bilirubin value?
A：High natural bilirubin is a genetic problem.
Medically known as Gilbert's syndrome （GS）.
The high level of bilirubin in the patient is due to the low activity of the liver Glucuronosyltransferase enzyme, which is unable to convert bilirubin to excretion via bile.
This is a natural genetic defect that does not affect health, and there is currently no medicine to treat it.
Q-46. Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） for iron deficiency anemia?
A：The liver is the metabolizing organ of human heme.
The catabolism of aging red blood cells will form bilirubin and iron.
Among them, bilirubin enters the gallbladder via bile, and then passes through the duodenum to be excreted from the body.
Iron combines with liver proteins to form Ferritin storage; and provides iron needed for the synthesis of new heme.
Therefore, the liver should not suffer from iron deficiency under normal metabolism and general diet.
Sometimes it is not easy for doctors to find out the cause of iron deficiency anemia.
As a result, patients often take long-term oral iron supplementation, which cannot be effectively cured.
At the same time, general chemical iron is not easily absorbed by the human body, resulting in limited therapeutic effects.
In the past, there has been a lack of effective drugs to treat liver disease in the world, and it has been unable to effectively improve the metabolism of the liver.
Although Silymarin is a world-recognized ingredient for liver maintenance, its low oral absorption rate is the bottleneck.
Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） effectively breaks through the problem of absorption rate.
And meet the qualified product of the United States Pharmacopoeia dissolution rate （>75%）.
Although Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is not a treatment for iron deficiency anemia.
Provide possible solutions
1. Continuous oral iron
2. It is recommended to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） in combination to improve liver function.
Take the two together or allow to try.
Suggested dosage： 1 or 2 capsules each time; 2 or 3 times a day.
After taking it for a period of time, ask the doctor to check whether the iron deficiency condition has improved.
Q-47. Can patients with immune system disorders take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A： Whether the patient is a symptom caused by an abnormal immune system, it is recommended to consult a doctor for diagnosis.
Many people ignore the importance of the liver in regulating the immune system.
1. The liver is the body's first immune organ.
2. The liver has the largest Mononuclear phagocyte system （MPS）, which can immediately swallow invading bacteria or viruses.
3. The liver produces albumin （Albumin）; albumin is the main component of plasma protein.
4. The liver is responsible for the production of 80-90% of the raw materials of globulin （Globulin） required by the immune system's second line of defense immunoglobulin antibodies.
Antibody production：
When the liver, the first line of defense of the immune system, cannot completely deal with the invading bacteria or viruses, it starts to produce antibodies for the second line of defense to help deal with the invading bacteria or viruses.
Therefore, the production of antibodies requires at least 14 days.
5. The liver is responsible for regulating immune tolerance to identify self or foreign proteins.
Therefore, the long-term unhealthy liver cells will affect their immune recognition ability.
When the recognition is wrong, the autologous protein is recognized as a foreign protein and the antibody is induced to attack the autologous protein.
For example： rheumatoid arthritis, lupus erythematosus, psoriasis, and other unknown diseases.
Generally, for immune diseases caused by unknown causes, unless there is a research report, it is not easy to diagnose the cause, and there is no ideal drug treatment.
It should be understood that the liver plays an important role in immune regulation.
Taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） is correct.
Patients suffering from immune abnormalities for many years.
Patients should be patient when taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
It takes a long time for the liver to heal itself and mediate.
Suggested long-term dosage： 2 capsules each time; 2 or 3 times a day.
The patient observes whether the symptoms are gradually slowing down, and if necessary, asks a doctor for a follow-up examination.
Especially during the epidemic period （during the COVID-19 virus epidemic）, it is more important to maintain the normal functioning of the liver and strengthen the liver's ability to swallow viruses.
Q-48. My gastrointestinal function is not good for a long time, and I am prone to bloating and indigestion. Sometimes I still can't improve it after taking gastric medicine for a long time.
Can I take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）?
A： The digestion and absorption of food are related to the liver; especially oily foods.
Because liver cells secrete bile to transport fat-soluble metabolites into the gallbladder for storage.
When eating, it stimulates the gallbladder to contract and inject bile into the duodenum.
At this time, the bile is mixed with the food processed by the stomach, which can emulsify oil to help digestion and promote the absorption of nutrients.
If the liver is poor, the secretion of bile will be lacking, and the liver is prone to inflammation, which will affect the quality of bile.
Especially the emulsification and absorption of oily foods are prone to flatulence and indigestion.
Stomach medicine alone may improve some symptoms.
If the patient can take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） together to promote the secretion of bile, it should be further improved.
Suggested dosage：
1. In severe cases; 2 capsules each time; 3 times a day; either before or after meals.
2. After improvement; long-term maintenance of health care; 2 capsules each time; 2 times a day.
Long-term use of Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） and gastric medicine should improve the problems of flatulence and indigestion.
However, patients should still cooperate with doctors for follow-up treatment.
Q-49. The patient has had gastrointestinal and flatulence problems for many years and has been taking gastrointestinal medicines for a long time.
Recently, the patient was introduced by the attending physician to take Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）, and her symptoms suddenly improved a lot, and she felt that the effect was better than gastrointestinal medicine.
Why can Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン） improve gastrointestinal function?
A： Bile is the indispensable key to food digestion.
Bile is secreted by liver cells.
If the liver is good, the quality and quantity of bile secreted by the liver will be improved.
When the fat-soluble waste is transported to the liver to be detoxified and metabolized, bile is produced, and good bile enters the gallbladder more smoothly.
When the gallbladder contracts and drains bile into the duodenum, it helps the digestion and absorption of food.
Especially fat-soluble foods and fat-soluble vitamins.
Therefore, when the liver function improves, the amount of bile secreted by the liver cells increases and the quality is good.
Therefore, the digestion and absorption function of the gastrointestinal tract is improved at the same time, and sometimes the recurring cholecystitis problem will be relieved.
Therefore, patients who take gastrointestinal drugs for a long time may be caused by poor liver function after the doctor's diagnosis.
The patient's gastrointestinal function will also improve after taking Silymarin （Hepana min | NO.1 | Milk Thistle | シリマリン）.
Suggested dosage：
1. Early stage; 2 capsules each time; 3 times a day. Take 30 minutes before meals.
2. After stabilization; long-term health care maintenance; 2 capsules each time; 2 times a day.